This is the website of the dos Reis Lab research group @ QMUL. You can contact us at

Research in the dos Reis Lab is focused on the development and application of statistical methods in phylogenetics. We are particularly interested in using Bayesian statistics to infer times of species divergences (that is, in placing geological times of divergence on the Tree of Life), and on methods to measure the strength of natural selection in molecular sequences. You can see examples of our research in the Key Publications below.

Our Research in the Media

Our research has been highlighted in the media an in textbooks! You can see some examples below:

Key Publications

  • A species-level timeline of mammal evolution integrating phylogenomic data
    Sandra Álvarez-Carretero, Asif U. Tamuri, Matteo Battini, Fabrícia F. Nascimento, Emily Carlisle, Robert J. Asher, Ziheng Yang, Philip C. J. Donoghue, and Mario dos Reis. (2022) Nature, 602: 263–267.
    DOI: 10.1038/s41586-021-04341-1 RedCube (no paywall):

  • A mutation-selection model of protein evolution under persistent positive selection
    Tamuri, AU, and dos Reis, M. (2022) Molecular Biology and Evolution, 39: msab309.
    DOI: 10.1093/molbev/msab309

  • Bayesian molecular clock dating of species divergences in the genomics era
    dos Reis M, Donoghue PCJ and Yang Z. (2016) Nature Reviews Genetics, 17: 71–80.
    DOI: 10.1038/nrg.2015.8

  • Uncertainty in the timing of origin of animals and the limits of precision in molecular timescales
    dos Reis M, Thawornwattana Y, Angelis K, Telford M, Donoghue PCJ and Yang Z. (2015) Current Biology, 25: 2939–2950.
    DOI: 10.1016/j.cub.2015.09.066

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Updated July 2022